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The null distribution of the number of breaks with a given chromosomal feature within 6 kb was determined by randomizing the location of break sites and determining the distance between these random breaks and the chromosomal features.
One event could be the textathlon, which would involve high-speed texting while skiing, with random breaks for shooting, of course.
Heat-induced fragmentation of RNA introduces mostly random breaks into the phosphodiester backbone.
The matched RESs in their 500-bp-long flanking sequences were removed as random breaks [ 23].
Finally, reliably detecting DSBs is confounded by random breaks occurring in vitro during DNA isolation.
The random breaks are reassembled in the original order about 82%% of the time across all 5 libraries (Table 3).
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"Clearly, there's a huge difference between a random break-in and, say, an ex-boyfriend breaking into an apartment to get his stuff," Mr. Holovaty says.
The former induces DSB and random break sites on DNA, whereas the latter induces SSB and only one specific break site.
In Multi-DB+, we introduce a technique called random break into Multi-DB; in Multi-DB++, we introduce a technique called random walk into Multi-DB+.
Electro-induced break junction (EIBJ) can generate an instantaneous and random break, but to obtain reproducible and stable devices it is very important to control the width of the nanogap [7, 8].
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