Exact(11)
The histological assessment of the organs demonstrated only random alterations (accompanied by only sporadic apoptosis) further reinforcing the perception that the recorded exacerbation in circulating markers in P-DIE (vs. P-SUR), although statistically significant, was not immediately indicative of a lethal organ failure in the young OF-1 mice.
From oulipean concepts that fuse random alterations to human generated language, to flarf poetry, where a writer mines the internet for errors and random speech, there continues to be a widening array of ways to build something mind-boggling out of the most basic elements.
These lesions may also co-evolve with random alterations that have little biological impact.
Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects.
A recent SNP-based survey [1] of 3,131 copy-number profiles derived from over 26 different types of cancer has provided a dramatic illustration of the power of high-throughput techniques in distinguishing random alterations in the genome from those that may have a direct impact on tumorigenesis.
Aging may be accompanied by random alterations of the genome that could accumulate and increase the vulnerability for cancer-specific alterations [ 43].
Similar(49)
The mutation operation is the occasional random alteration of the genes in a chromosome.
Random alteration of the value of a specific variable has a similar effect to take out of this variable.
In another word, biological networks are robust to random alteration of nodes but sensitive to hub removal.
Non-random alterations are statistically significant relative to our null model and therefore are candidate regions of interest.
We searched for non-random alterations in the frequency of contacts between the PADI3 gene promoter and PIE in living keratinocytes by the use of Chromosome Conformation Capture (3C, Fig. 4) [44].
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