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Is natural history a story with a plot, or just a random accumulation of anecdotes?
It is found that random accumulation of vapor phase particles creates pores that are inclined away from the incident direction at angles dependent on the ratio of the parallel and perpendicular accumulation rates.
In particular, attenuation of vertically transmitted viruses was a consequence of the random accumulation of deleterious mutations, whereas horizontally transmitted viruses experiencing similar bottlenecks did not suffer the same fitness losses because effective bottleneck size was actually determined by the number of host individuals.
The random accumulation of founder effects does not permit the accurate identification of all possible founder lineages in the European Roma, since many of them may be present at low frequencies in the Balkan Roma but absent due to loss in Roma from other regions in Europe.
Assuming random accumulation of mutations, the degree of divergency should then be age-related.
Otherwise, no-longer-useful dental-specific genes might have been invalidated through random accumulation of mutations.
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But their efforts also encompassed immense, pseudo-encyclopedic, seemingly random accumulations of still or video images.
The non-random accumulation of mutations and the excess of corrected synonymous mutations (Table 1) are consistent with purifying selection operating in the evolution of mutagenized populations.
These data, together with the non-random accumulation of mutations along the viral genome, strongly suggest that purifying selection operates on FMDV in the course of replication under enhanced mutagenesis.
Using our own and TCGA data we then evaluated five possible models to explain the selection for non-random accumulation of LOH in ovarian cancer genomes: 1. Classic two-hit hypothesis: high frequency biallelic genetic inactivation of tumour suppressor genes.
In one case, the origin of six species of Taterillus gerbils within the past 0.4 million years has been accompanied by numerous large chromosomal changes and the non-random accumulation of LINE-1 elements, with the most recently diverged species showing the greatest amount of LINE-1 accumulation [ 18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com