This change in phenotype is characterized by a raised expression of type I collagen and a decrease in type II collagen expression.
Furthermore, NADPH oxidase activity was significantly increased, with raised expression of NOX1, NOX2, NOX4, p38MAPK and MnSOD, in the renal tissue of hyperoxaluric rats compared to control.
Then, the raised expression of musclin could lead the hypertension to be more serious.
In hormone-dependent tumours, Gd has been described to have various effects through reduced expression of oncogens and raised expression of tumour suppressor genes.
Various classes of polyphenols have been shown to post-transcriptionally regulate levels of mRNA containing AU-rich elements by raising expression of RNA binding proteins [ 46– 46].
Thirdly, where hepcidin levels are raised, expression of the iron transport protein ferroportin in enterocytes is suppressed such that release of absorbed iron into the bloodstream is restricted.
Our results show that most (eight out of nine) synovial sarcomas clustered as a single group based on their gene expression portrait and that this cluster was characterised by the raised expression of a set of 48 genes.
Only in a few tissues, such as gills and muscle, did line 1 show raised expression of the transgene, e.g. a sevenfold higher transgene expression in the gills when compared with the other organs examined (Fig. 2A).
The raised expression of the snoRNA in INI mice could impact on other genes not quantified in this study; indeed, mbii52 has been implicated in the splicing of a further five brain transcripts (Kishore et al., 2010).
Raised expression of Pygo1, and to a lesser degree of Pygo2, was seen in stromal cells, and significant nuclear staining was detected in essentially all cells of the developing kidney for both proteins.
