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This behavioral ambiguity however raises a significant challenge to the design of strategies to therapeutically target PML.
The decision to shut down and decommission both reactors in Lithuania before termination of design period raises a significant challenge for the treatment of accumulated SNF.
This result supported the theory of crack arrest in the fillet area of crankshafts and raises a significant challenge to the use of the surface crack failure criterion due to its inconsistent correlation to two-piece failure.
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Varian's disappointment at Postponed's failure to raise a significant challenge was palpable.
These members raise a significant challenge to crash simulations that involve a large number of contact analyses.
All these detrimental effects associated with multitasking - affecting not only students who willingly multitask but also those nearby - raise a significant challenge for instructors: can the advantages brought about by the inclusion of mobile devices in a classroom setting still be harnessed, while avoiding the potential for distraction they may pose, and how?
Analysis of this rapidly accumulating wealth of ss-rRNA sequences has raised a significant challenge – how to balance the desire for high quality methods with the need for automation to keep up with the sequence onslaught.
The Government of Viet Nam recognizes that some segments of society remain underserved despite its best efforts, raising a significant challenge to the achievement of the government's education targets.
Independent historical changes in genome architecture in diverse lineages raise a significant challenge to the idea that genome size is finely tuned to achieve adaptive phenotypic modifications and suggest that attempts to use phylogenetic analysis to infer ancestral genome sizes may be problematical.
This raises a significant concern regarding surface modification.
However, close examination of the document raises a significant concern.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com