Altogether, the RNA-seq data raised the hypothesis of a specific dysregulation of EphB1-induced reactivity genes (Fig. 6d f).
These studies raised the hypothesis that a laminin-5-derived peptide can promote wound healing by accelerating re-epithelialization in vivo.
Yeast and fly studies revealed an interaction with the counterparts of human Ataxin-2, a gene whose polyglutamine repeat expansion is associated with spinocerebellar ataxia type 2. This finding raised the hypothesis that repeat expansions in ataxin-2 may associate with diseases characterized by TDP-43 pathology such as ALS.
The observation that muscle and nerve inexcitability was an early phenomenon predictive of muscle weakness raised the hypothesis of a channel dysfunction that was subsequently confirmed by alternative experiments [53].
Becker raised the hypothesis that a significant part of that variance was related to the quality of those investments and therefore to an imperfect measurement of the amount invested by each individual.
The above mentioned bioinformatics study by Ponting et al. also raised the hypothesis that archaea might contain presenilin-like proteins [19].
The discussion on TTR/A-Beta interaction and consequent inhibition of aggregation and toxicity reduction raised the hypothesis that mutations in the TTR gene or conformational changes in the protein induced by aging, could affect the sequestration properties.
These data raised the hypothesis that myosin Va-mediated translocation of granules only occurs after detachment of Slac-2c/MYRIP from microfilaments, possibly due to the calpain-mediated cleavage of Slac-2c/MYRIP actin-binding C-terminus [56].
In Bin-treated MDCK-Cpm1 cells we could detect many autophagosomes that were either isolated or initiating fusion with the enlarged autolysosomes induced by Bin, which raised the hypothesis of an autophagy induction.
The observation that these mutants behaved as wild type parasites throughout the entire Leishmania life cycle, raised the hypothesis that a second mitochondrial TXN, different from LiTXN2, would exist.
Instead, it raised the hypothesis that saxagliptin may reduce the risk of major adverse CV events.
