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But when it happens to someone who's been raised cut off from the rest of society like many of these people have, it can be doubly traumatic.
That "Born N Raised" cut off Khaled's album?
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As shown in Figure 1A, the global low expression of miRNA targets did not vanish when we changed methods or cut-offs, and the RR values actually decreased with the raised cut-offs.
Raising TLC cut off values to improve sensitivity and enable TLC to be used as a better screening tool has been previously proposed by adult studies in Uganda and Kenya [ 17, 18].
Some higher commitment, some force of national will, is required especially while quisling banks raise interest rates, cut off small-business credit and plead "contract" while paying obscene bonuses even as, like Uriah Heep, they tug forelocks and plead humility in the face of censure.
Sensitivity and therefore utility of TLC to identify immuno-suppressed children may be improved by raising the TLC cut off levels across the various age categories.
In this cohort, only 10 women changed from Luminal B/HER2- to Luminal A by raising the Ki67 cut off from 14%to20%0%.
For age category <12 months, raising the TLC cut off from WHO 4000 cells/mm3 to 7000 cells/mm3 improved the sensitivity from 25%to71%1%, but decreased specificity from 100%to73%3% (Table 4).
Similarly for age group 12-35 months, raising the TLC cut off value from 3000 cells/mm3 to 6000 cells/mm3 improved the sensitivity from 23%to65%5% accompanied by a decreased specificity from 98%to62%2%.
For age category 36-59 months, raising the TLC cut off value from 2500 cells/mm3 to 4500 cells/mm3 would improve the sensitivity from 33% to approximately 60%.
In Kenyan adults, raising the TLC cut off value from the recommended 1200 cells/mm3 to 1900 cells/mm3 resulted in improved diagnostic utility for predicting CD4 < 200 cellsensitivityitivity 81%, specificity 90%, PPV 90%, NPV 80%) [ 17].
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