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Two important guidelines were that those enrolled in the trials should have values of the nutrient marker of interest at the lower end of the nutrient-health outcome relationship, and then be given in sufficient enough amounts to raise the marker to the upper end of the relationship.
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One hopes that these and future initiatives will raise the level of tumor marker research to that of therapeutics, so that clinicians, and patients, can reliably apply the long-sought concepts of 'personalized cancer care'.
In his commentary, Ian Cree [ 5] discusses how technical improvements in tests to detect circulating tumor markers, and indeed the potential for some molecules to act as general tumor markers, raise the possibility of blood test-based general screening for multiple cancers - in effect, screening for who to screen.
But the use of deltaC as a marker does raise the question of whether this ligand is involved during angptl-mediated notch activation.
If validated, findings such as these may contribute to increased molecular knowledge of basic glioblastoma pathophysiology and raise the possibility of detecting metabolic marker patterns associated to early treatment response.
This study also found that patients experiencing a defined reduction in both bone markers suffered fewer events than in those with reduction in only one marker, raising the possibility that an index comprising more than one bone marker may add further predictive value.
This promising data raises the question if these markers can be used as biochemical markers of psychosocial stress and the authors called for more research to confirm their findings.
There are certain phrases that add up to the mantra of the Lions tour: laying down a marker; raising the bar; all doing the same thing; equal opportunities.
He raised the awareness that other marker procedures should be considered to prevent model bias.
The ubiquitin-dependent vacuolar delivery of the Golgi marker raised the question as to whether the transport of this chimera occurs through the biosynthetic vacuolar transport route via the TGN/EE and the MVB/LE.
Optimization of the GS model raises the question of whether marker effects should be estimated from data on the pure lines or crossbreds.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com