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However, recent studies have also identified complex physical interactions between PARP-1, PARG, and other nuclear proteins [34], [35], and these findings raise the alternative possibilities that reduced nuclear PARG protein could influence PARP-1 activity by through these or other, more indirect interactions.
However, if this were the case, it would raise the alternative question of how d-serine is degraded in the cortex.
These observations raise the alternative possibility that the role of TAK1 in vivo might be to stimulate the formation of these polyubiquitin chains, rather than to phosphorylate the canonical IKK complex directly.
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But it also raised the alternative of a different kind of Britain, rooted in solidarity and collective action.
It raised the alternative of a different Britain from the greed and individualism of the Thatcher years, rooted in solidarity and collective action.
He also found that when he raised the alternative reward to $20, every single addict, of meth and crack alike, chose the cash.
Because applying the tax break to only one class of taxpayers would require legislative approval in Albany, other Council members raised the alternative possibility of granting it to all property owners.
And it raised the alternative of a different kind of Britain, rooted in solidarity and collective action, to the individualism and private greed of the Thatcher years - which continues to shape our times.
This mechanism is not activated unless DNA replication has been initiated (Murakami and Nurse 2001), raising the alternative possibility that a DSB checkpoint exists in C. cinerea but is bypassed in msh5-22 if DNA replication is never initiated.
However, the finding that 5% of the wild-type level of Smc2 persist in Smc2-depleted chicken DT40 cells (Ohta et al. 2010) raises the alternative possibility that traces of condensin suffice to drive condensation from prophase to metaphase but not for providing the stiffness required for chromosome segregation upon anaphase onset.
Recent findings raise the possibility of alternative mechanisms through which the DMH activates BAT thermogenesis.
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