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"raise great concerns" is a correct and usable phrase in written English.
You can use it when something has the potential to cause significant worry or anxiety. For example: The recent reports from the Centers for Disease Control have raised great concerns about the spread of the virus.
Exact(1)
Concerning their use in biological systems, lack of solubility (both in organic solvents and aqueous solutions), formation of thick and inhomogeneous bundles, circulation half-life of 3 to 3.5 h [4], and biocompatibility and immunogenicity limitations raise great concerns.
Similar(59)
The swarms of the vessel-transported American comb jelly (Mnemiopsis leidyi) that spread across the Mediterranean from Israel to Spain in 2009 raise great concern because of their notorious impacts on the ecosystem and fisheries [ansamed.info and 360].
The effects of representative substances such as BPA and p-NP, in the scenario of environmental contaminants, raise great concern for the environmental risk to the health of the fetus.
In conclusion, the data reported here raise great concern for the environmental risk to pregnancy, indicating the need to develop more accurate tests for the protection of both the prenatal life and the development of the fetus.
Payments that raise greater concerns include those which attempt to induce hospitals to purchase a particular device or which provide financial incentives to use specific devices or meet quotas.
Extensive use of neonicotinoid insecticides has raised great concerns about their ecological risk.
The negative impacts of aggressive environment on the durability of concrete materials have raised great concerns in recent years.
Tea expansion, a typical process of regional land use and cover change (LUCC), has raised great concerns on regional sustainability.
The Refugee Council of Australia acting chief executive, Tim O'Connor, said the announced closure was welcome but "raises great concerns about the welfare of the almost 1,000 men Australia has kept there".
The Prism scandal, however, raised great concerns about the privacy of information and a co-founder of Pirate Bay, Peter Sunde, has a solution – a messaging service that encrypts information on both ends.
China's energy consumption experienced rapid growth over the past three decades, raising great concerns for the future adjustment of China's energy consumption structure.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com