Exact(4)
Methylphenidate, a dopamine and norepinephrine transporter blocker known to facilitate these cognitive processes at low doses, was hypothesized to interfere with memory storage at doses that may raise concentrations of these neurotransmitters to systemically disruptive levels.
This interaction may be related to the ability of bile acids to slow clearance and raise concentrations of corticosteroids [ 2, 3].
Moreover and as mentioned above, 5α-reductase is considered the rate-limiting step in the synthesis of allopregnanolone from progesterone in brain and so activation of AKR would not be expected to raise concentrations of this metabolite in vivo.
One explanation for the utility of fluoxetine and other SSRIs in the treatment of PMDD is their ability to raise concentrations of the neuroactive progesterone metabolite allopregnanolone in the CNS, an effect documented in the brains of male rats (Uzunov et al., 1996) and mice (Pinna et al., 2003) and in both male and female human CSF (Uzunova et al., 1996).
Similar(56)
It is noteworthy that a diminished SFR concentrates the salivary proteins, thereby expressing raised concentrations of salivary proteins including IgA and IgG.
They considered forest fires, but found no evidence of raised concentrations of charcoal in the lake bottom.
nytimes.com/shiftingcareers DOT EARTH: Carbon Dioxide Nourishes Plankton A new laboratory study has shown that some types of plankton thrive in water with a low pH created by greatly raising concentrations of carbon dioxide.
So far no tritium has been found in any drinking water wells, nor have raised concentrations of radioactive material been found in the river, the source of the plant's cooling water.
Enzyme supplementation raised concentrations of total volatile fatty acids in rumen fluid with an associated increase in the proportion of acetate and total bacteria counts.
Furthermore, co-dopants are found to influence Young's modulus according to their cationic properties, their effect on oxygen vacancies and their effect on the amounts of phases retained: Young's modulus is decreased by cationic radii larger than that of Zr4+, increased with raised concentrations of oxygen vacancies, and decreased with an increased presence of m phase.
One such factor appears to be raised concentrations of plasma total homocysteine (tHcy).
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