Sentence examples for raft leading from inspiring English sources

That is, when all factors are taken into consideration, the original way any thing appears is no longer unambiguously present, but it restored as a raft leading to all other rafts, including itself, as ineradicable aspects of all reality, of any reality.

This moves receptors out of lipid rafts, leading to a lower level of response.

As DRMs cannot distinguish L-rafts (leading edge rafts) and U-rafts (uropod rafts), our data suggest that flotillins are constitutive components of lipid rafts while other molecules such as the PI3K require chemotactic stimulation for recruitment to these signaling platforms.

We show here that ATLs inhibit PI3K/Akt signaling by displacing Akt and key enzyme regulators from lipid rafts, leading to Akt dephosphorylation and apoptosis.

In addition, we demonstrate that the cytoplasmic region of CD26 had a crucial role in MPM tumour biology through its linkage to SSTR4 and SHP-2 PTP in cell membrane lipid rafts, leading to cytostatic effects in MPM cells without direct association of ECM to CD26.

This result suggests that Rh2 is a novel lipid raft disruptor leading to Fas oligomerization and apoptosis.

This translocation of Fas/CD95-DISC into raft clusters, leading to Fas/CD95-mediated apoptosis independently of FasL/CD95L, provides a new molecular insight into leukemia chemotherapy and in the triggering of death receptor-mediated apoptosis.

Loss of Dab2 expression may thus shift localisation of TGF β receptors to lipid raft compartments leading to increased MAPK signalling and EMT.

Due to their reduced LCB and ergosterol content Δ ZtCBR1 spores may have been less frequently able to produce lipid raft domains, leading to less frequent hyphal extension resulting in slower overall growth.

Although these anti-tumour effects were blocked by coexpression of CD26, ligation of CD26 molecules by humanised anti-CD26 mAb induced lipid raft aggregation, leading to the activation of the cytostatic signalling molecule SHP-2 via clustering of SSTR4, which provides a platform for signalling events associated with multimerisation of SSTR4 molecules.

Examines the endocytic trafficking of activated β-ARs and Gαs, and find that Gαs is endocytosed by a lipid raft-mediated mechanism leading to a putative reduction in cAMP signalling.