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This appears to be due to a failure of the threonine form of the receptor (FcγRIIB-232T) to partition to lipid rafts, perhaps due to the polar nature of the threonine, or disruption of a protein sequence necessary for raft entry (16, 19).
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Despite his raft of entry permits, Abdulla says he was arrested half a dozen times in Africa.
We asked whether caveolin-2 might be associated with the inclusions of each of the ten chlamydial strains and species that we had previously assessed for raft-mediated entry and for inclusion-associated caveolin-1 [ 19].
However, EVs including both MVs and exosomes have been proposed to enter target cells through multiple mechanisms, including ligand-receptor-mediated [ 20, 21], or lipid raft-mediated entry [ 22, 23], with EV fusion and uptake greatly influenced by surrounding pH levels [ 24].
Work on T-cell activation domains [11,12] has shown the functional necessity for these lipid species to cluster into domains [13] and the apparent role of lipid rafts in pathogen entry into cells [14,15], while recent reports have also revealed an association between membrane rafts and the haemagglutinin of influenza viruses [16].
The Zelda postman his real name, we may never know it appears in a raft of franchise entries, dating back to 2000's Majora's Mask.
The Zelda postman – his real name, we may never know it – appears in a raft of franchise entries, dating back to 2000's Majora's Mask.
Recent studies have suggested the critical role of lipid rafts in filovirus entry into the host cells.
Indeed, transient disruption of macrophage lipid rafts decreased the entry of promastigotes, but not amastigotes, into macrophages (P<0.001).
The monocytic cells also consist of Hsp70 and Hsp90 which are important components of the lipid raft in the DENV entry receptor complex [ 38, 39].
For HBV, the cellular membranes and lipid rafts are particularly involved in viral entry; for HCV, lipid rafts additionally are required for formation and/or maintenance of HCV viral replication, virion assembly, and virion release from the host cell.
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