Definite FXTAS requires the presence of the major radiological sign, white matter disease in the MCP, in addition to tremor and/or ataxia in a premutation carrier.
Of special interest, cognitive decline in patients with radiological abnormalities (white matter hyperintensities and global cortical atrophy) was associated with radiotherapy doses that are considered safe (< 2 Sv) [ 60].
Radiological signal changes of the white matter increase with age and were clearly seen in the present healthy control group.
They used an M.R.I. scan to measure brain volume and white matter hyperintensities, a radiological finding indicative of vascular damage.
Cerebral oedema is often the earliest radiological sign and it preferentially affects the white matter [ 5].
Quantification of water diffusion will improve the neuro-radiological assessment of a variety of gray and white matter disorders, including those involved in pain processing.
Of the 88 proven CAP patients, fever, increase of respiratory rate, CRP, white blood cells (WBC), cough, wheeze and radiological findings were statistically analysed.
Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological condition that involves a variety neurological manifestations and reversible white matter changes on T2-weighed MRI sequences.
Acute pyelonephritis was defined for every patient with all the following [ 16]: a) core temperature > 38°C; b) radiological evidence consistent with the diagnosis; and c) ≥ 10 white blood cells in centrifuged urine sample or ≥ 2 + in urine stick for white blood cells and nitrite.
Diagnosis of an intra-abdominal infection was made for any patient with the following symptoms [ 7]: core temperature >38°C or <36°C, white blood cells >12,000/μl, and pain on palpation or radiological findings consistent with an intra-abdominal infection.
