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Classic methods to establish antitumour effects of systemic agents, which rely on assessing changes in tumour size by radiological assessments, are no longer sufficient.
Clinical and radiological assessments were performed at regular intervals.
Clinical and radiological assessments were performed at the final follow-up.
Radiological assessments included an MRI before and at least 1 year after surgery (control exam).
At the final examination 8 weeks after fixator removal, the radiological assessments were made on AP and lateral X-rays.
Clinical and radiological assessments were performed at the 6th week and the 3rd, 6th and 12th month postoperatively.
Computer-aided design/computer-aided manufacturing (CAD/CAM) was also evaluated to estimate its efficacy with clinical and radiological assessments.
Clinical and radiological assessments were performed up to 52 weeks, with outcomes being measured by a blinded assessor.
Routine clinical and radiological assessments were performed at 3 and 6 weeks, also at 3, 6, 9 and 12 months.
The radiological assessments of realignment showed a reduction of listhesis from an average of 21.04% (standard deviation [SD] 5.1) preoperatively to 9.14% (SD 4.0) postoperatively (p < 0.001).
Clinical and radiological assessments were made at monthly intervals for the first 6 months and then at 2-month intervals for the next 6 months.
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