Sentence examples for radical mutation from inspiring English sources

This radical mutation is arguably more gruelling to watch than Kafka's descriptions are to read.

Perhaps the most radical mutation is the duplication of an entire set of chromosomes.

Such a radical mutation of heroism into the basest brutality is not often encountered in our daily lives, but it is a hallmark of soldiers' lives in war... Two officers are accused of the torture of Louima; 2 more are accused of beating him up.

Writing this week in the newspaper El País, José María Ruiz Soroa, a lawyer, argued that the stalemate in Catalonia had allowed the judiciary to take center stage and undertake "a radical mutation of the rules of the Spanish constitutional game," by criminalizing the independence drive.

In fact, there is an EspD-EspD protein interaction and a radical mutation in the C-terminus coiled-coil domain of EspD affects EPEC induced A/E lesion formation, EspA filament-mediated cell attachment, and EPEC induced hemolysis without affecting EspA filament biosynthesis [27].

Therefore, fairly radical mutations have to be applied in order to extinguish the biotin-binding activity of (strept avidin as previously reviewed [2].

SNPs causing radical mutations, such as premature stop codons or frame disruptions, were also identified (Additional file 10).

Of the amino acid changing mutations examined the majority were conservative mutations and the ratio of radical to conservative mutations was not significantly different for any of the variables tested due to the relatively small number of radical mutations.

Conversely, as species diverge the small number of radical mutations may be explained by the conservation of physiochemical properties, which are often conserved to maintain protein function even across evolutionary distant species [ 40].

Since the major determinant in oral cancers is the accumulation of genomic instability [ 31], and no obvious evidence was observed in radical mutations or gene expression, it is possible that the excess of somatic mutations in GTF2H5 may influence post-transcriptional regulation and correlate with tumor development.

For example, rs3736360 is a radical missense mutation in the HSPG2 gene and it is a 3' UTR SNP in the context of the overlapping gene LDLRAD2.