The realities of a new U.S. defense policy that is suddenly placed under radical budget constraints have not yet sunk in, say analysts.
Controlling for absorptive capacity, firm age, and firm growth, we find full support for the hypothesis that knowledge constraints spur radical innovation and partial support for the hypothesis that financial constraints spur radical innovation.
In order to do so, one must observe the constraints of "radical interpretation"—in particular, the "principle of charity," which states that a speaker's sentences should be interpreted in such a way that most of them are counted as truthful.
Coefficients of functional divergence that are significantly greater than 0 indicate site-specific altered selective constraints or radical shifts of amino acid physiochemical properties after gene duplication.
For cases in which other experimental constraints (hydroxyl radical footprinting for the P4 P6 domain and class I ligase; tertiary information from M on the P4 P6 domain) were available, these constraints were also included in the modeling.
DIVERGE performs the ML estimation of the theta type-I and type-II coefficients of functional divergence, based on the occurrence of altered selective constraints or radical shifts of physicochemical properties, respectively [ 27, 28].
Ruth Carnall, who was chief executive of NHS London until April, said that, in order to do that, Stevens would have to deliver the "radical transformation necessary" with resource constraints"the like of which we have not seen before, and in the face of public and political resistance to many of the changes currently proposed", such as centralising key services in fewer hospitals.
(Donald Davidson developed a similar line of thought in a less behavioristic idiom, speaking in terms of constraints on a "Radical Interpreter," who seeks "charitable" construals of alien speech).
Reviewer #1: The authors describe an improved method for using high throughput sequencing and tethered hydroxyl radical cleavage to obtain distance constraints for RNA modeling.
If θI or θII is significantly greater than 0, it means that site-specific altered selective constraints or a radical shift of amino acid physiochemical property occurred after gene duplication and/or speciation [ 103].
