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From 1997 to 2004, six independent experiments on mice and rats studied the effects of chronic radiation on brain cancer.
The effects of high dose gamma radiation on brain tissue are poorly understood, with both limited and major changes reported.
Studies on the effects of gamma radiation on brain tissue have produced markedly differing results, ranging from little effect to major pathology, following irradiation.
The MDA-MB-231-BR cell line is a subclone of MDA-MB-231 that selectively metastasizes to the brain, demonstrating that this combined targeting strategy may be applied to enhance the effects of radiation on brain metastasis in TNBC patients.
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Higher levels of DNA damage-induced γ-H2AX focinin brain of young animals may result in toxic radiation effects on brain, changes in memory and cognition, and even lead to increased frequency of brain tumors.
The study, by Tore Straume, the chief life scientist at Nasa's Ames Research Centre in California, looked at the effects of radiation on the brain, body and pregnancy.
Adlkofer described his experience with the EU-funded study REFLEX, which aimed to explore the effects of cell-phone radiation on the brain.
The differential effects of 200, 591, and 2,450 MHz radiation on rat brain energy metabolism.
The difficulty experienced trying to treat these tumors, combined with the highly toxic effects of radiation on the brains of young children, make alternative therapies highly desirable.
While significant advances in treatment have been made, with the 5-year survival rate for medulloblastoma at 70 80%, treating patients under 3 years of age still poses a problem due to the deleterious effects of radiation on the developing brain, and the median survival for patients with glioblastoma is only 15 months.
The work "builds on a notable amount of literature showing that space radiation produces negative consequences on brain and behavior," says Amelia Eisch, a neuroscientist at the University of Texas Southwestern Medicine Dallas.
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