The conclusion for oral cancer was based on only a few, mainly quite small studies that provided quantitative data.
For the majority of intermediate traits related to type 2 diabetes, the number of larger studies performed is quite small and studies in which heritabilities of several risk factors of type 2 diabetes were estimated in the same population are even scarcer (ESM Table 1).
As the data in group two are quite small, detailed studies have not been carried out.
However, since the association was significant only after the follow-up at two years and the PPVs of bone loss for radiological progression were quite small, further studies are required before this can be established.
Two other studies, namely those by Balada [ 16] and Wipff [ 17] and colleagues, failed to find an association with this polymorphism, but the number of cases and controls in these studies was quite small (the Balada study included only 54 cases and 55 controls, whereas the Wipff study included 121 cases and 103 controls).
Even though numbers of subjects in this study are quite small and the study duration is short, physical performances are statistically improved by participating in the Thai dance.
However, the sample size for this study was quite small and larger studies are needed.
Second, the overlap between differentially expressed genes identified in different studies is quite small, even on studies aimed on the same phenotypes and tissues.
While there seem to be some differences in the levels of ORF1p and ORF2p expression depending on the grade of DCIS, the number of DCIS cases was quite small in our studies, and further studies are required to evaluate this.
Most studies of moderate inflation find that its costs are quite small, but a study of elections in thirteen European countries from the nineteen-sixties to the nineties found that voters were far more likely to toss out politicians when inflation rose than when unemployment did.
