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It was an unusually quiet trial, what we saw of it.
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Garvey's emotion transforms the quiet trials of everyday life into a magical thing.
Percent correct performance shown for NBN, AM, and Quiet trials.
When SS treatment was discontinued (P1 P4), performance on Quiet trials returned to baseline indicating that tinnitus had disappeared.
Behavioral evidence of tinnitus was defined as a significant shift in behavior only on Quiet trials (percent correct below the 99% confidence interval established during baseline testing).
Since the rats were trained to respond left to a steady NBN vs right to fluctuating AM noise or Quiet, we expected that if a rat developed SS-induced tinnitus, it would only shift its response on Quiet trials from the right side (associated with Quiet) to the left side (associated with a steady NBN) as previously discussed (Stolzberg et al., 2013).
However, when the rats were treated with SS, performance dropped to 50% or less only on Quiet trials, that is, rats shifted their response preference from the feeder associated with Quiet to the feeder associated with a continuous NBN, behavior indicative of tinnitus.
Similarly, Prosperini et al. [ 18] found a significant reduction in the COP path length (i.e., the overall length of the trajectory followed by the COP during the quiet standing trial) in a crossover study that analyzed balance before and after a period of 12 weeks (48 30-minutes sessions) of partly supervised home-based Wii activity in 36 patients with MS divided into two groups.
Those regions were quiet during trials in which subjects actually pushed the button.
Balance control during the quiet standing trials is characterized via both traditional and random-walk sway parameters [ 100, 101].
Balance control during the quiet standing trials was characterized via traditional sway parameters including average sway velocity (mm/sec), total stabilogram ellipse area (mm), and anterior-posterior (AP) sway range.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com