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The responsibility of handling these dead cells falls on phagocytes of the immune system, which surveil their surroundings for dying or dead cells and efficiently clear them in a quiescent manner.
It is thought to do so in a quiescent manner, failing to produce a significant oxidative burst and to activate the innate immune system [ 20– 23].
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Time-lapse imaging revealed that endothelial cells lacking Pten display protruding filopodia in a highly dynamic manner, whereas endothelial cells in siblings remain quiescent (supplementary material Movies 1, 2 and Fig. S1).
In response to both PTH 1-34) and PTHrP 1-34), quiescent MCF-7 cells proliferated in a similar dose-dependent manner (1.6-100 ng ml-1).
For example, MAL, a cofactor of the transcription factor SRF, cycles dynamically between the nucleus and cytoplasm in a manner regulated by its binding to G-actin in quiescent cells (Miralles et al., 2003; Vartiainen et al., 2007).
Little attention was given to investigate the quiescent interfacial method itself and the physical chemistry involved in a comprehensive manner compared to the well-studied mixed and static systems.
When Rb was acutely inactivated in quiescent Rb Lox / Lox MEFs, p107 was not immediately upregulated in a compensatory manner, and the cells re-entered the cell cycle [ 20].
In the rat, we have shown that in addition to classical GPCR-mediated pathways, this ERK pathway, in a cause-and-effect manner, facilitates myometrial contraction, and plays a distinct role in the switch from the quiescent phase of pregnancy to a more contractile phenotype at the end of pregnancy [6], [7].
All three TGF-β isoforms suppressed TEB formation (in a reversible manner), causing the ends of the ducts to take on the appearance of growth-quiescent ducts [ 9].
The first aim of the current study was to determine whether a chronic increase in cellular oxidative stress in quiescent muscles of adult Sod1 −/− mice leads to the activation of redox-regulated adaptive responses in a similar manner to that seen in quiescent muscle of old WT mice.
Sensibilities quiescent then are more vocal now.
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