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Exact(8)
Oral leukoplakia (OL), which is the most common among these lesions, is defined by the World Health Organization as "a white plaque of questionable risk having excluded known diseases or disorders that carry no increased risk for cancer".
Similarly, TZDs have been associated with a questionable risk of bladder cancer [ 149- 151].
This would present unnecessary and ethically questionable risk to the patients and was therefore decided to not be appropriate for this study.
Given that IRBs and DSMBs are assembled to determine the risks to study participants, product contaminants of questionable risk may be too ambiguous for clear direction.
The small number of studies and patients included, as well as the questionable risk of bias, however, points out the demand for well-conducted trials before general recommendations can be derived.
Oral leukoplakia (OL) is defined as "A white plaque of questionable risk having excluded (other) known diseases or disorders that carry no increased risk for cancer", which is the best-known potentially malignant disorder of the oral mucosa [ 3, 4].
Similar(52)
Incentive-based pay packages, critics say, invited questionable risk-taking at the American International Group and the nation's big banks.
Lawmakers and regulators have sought to rein in compensation at financial firms, blaming large incentive-based pay packages for the questionable risk-tasking during the market boom.
S&P, which cut to A+ and kept it on negative watch, cited management "miscues" and questionable risk-management procedures at Merrill, and called the write-downs "staggering".
Examining the randomized studies only or all the studies did not modify the results, with a questionable risk-benefit balance and no impact on mortality despite an analysis performed on more than 32 000 patients.
However, the reliability of evaluation results has remained questionable without risk adjustment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com