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The members of the CERC carried out extensive data cleaning, and queries were addressed to the investigators for questionable or missing data.
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We reviewed the genotypes for the presence of double recombinants over short genetic distances, and questionable genotypings or missing data were repeated.
This approach suffers from activity gaps or missing data.
Invalid or missing data were excluded.
The percentages of gaps or missing data were 3%gaps/20%% missing data for trnL-trnF, 3%gaps/40%% missing data for trnS-trnG, and 15%gaps/29%% missing data for psbA-trnH.
ECOG indicates Eastern Cooperative Oncology Group; % Missing, the proportion of unknown or missing data within the validation set.
Codons with gaps or missing data were ignored.
Daily frequency tables were revised for all variables and the investigators were queried when data values were either questionable or missing for required fields.
The handling of missing data is questionable in that patients with missing data who appear to have been omitted, thereby suggesting a complete-case analysis that has been shown to be a methodologically flawed and biased in the development of prediction models (Clark and Altman, 2003; Burton and Altman, 2004; Moons et al, 2006).
This increases the chance for missing data or unreliable data.
NA marker monomorphic or containing too much missing data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com