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Genes of the Argonaute (AGO) and Dicer-like family are encoded by Trichomonas and hence suggest the existence of functional RNA interference mechanisms [ 5, 14], although other studies question the functionality of identified miRNAs in this parasite [ 19].
Mr. Maher would like his house to question the functionality of architecture.
It would (quite legitimately) call into question the functionality of the German model — based in part on the involvement of state institutions and the particularly intimate role of banks in company management — that neither big party is ready to challenge as creed.
Nonetheless, the trend in clinical events observed in STALWART is concerning in light of the results of ESPRIT and SILCAAT that question the functionality of CD4+ cells induced by IL-2.
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This apparent lack of inherent selectivity questions the functionality of the PDZ binding space if it were the only parameter involved in organizing PDZ-protein interactions.
Finally, we questioned the functionality of a peripheral and an intrinsic membrane protein, and demonstrated that both proteins were active when produced in this system.
Finally, we questioned the functionality of STX-SC-derived myelin focusing on the ability to re-assemble paranodal Caspr and nodal voltage-gated Nav proteins, as endogenous Schwann cells do (Black et al., 2006).
This is also a question of the functionality of the upper layers, that is, how the source, relay, and destination are set up and how spectrum resources allocated.
The finding that multiple T3E genes are affected by DNA rearrangements raises the question of the functionality of these genes within the repertoires.
Hence, the question of the functionality of DNA-topological regulators and of their links with gene expression regulation is still open.
In some cases, the absence of specific domains (e.g. RipC1CMR15 lacking the C-terminal half present in other RipC1 alleles) raises the question of the functionality of the corresponding protein.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com