This review identified a substantial number of primary empirical studies contributing data to questions of uptake.
However, this is an important topic that directly relates to the question of technology uptake in health care systems and should be analyzed in future studies.
For example, liposomes and polymeric micelles accumulate readily with or without target-mediated ligands; however, the question of whether uptake is specific for the intended target is not always addressed.
I am most interested in applying basic ecological insights (e.g., feeding and digestive strategies, animal/substrate interactions) to toxicology in order to provide greater environmental realism to questions of pollutant uptake and toxicity.
These simple experimental systems have been used to explore general questions of proton uptake by proteins, such as the functional value of an initial proton acceptor, whether an initial acceptor must be surface-exposed, which side chains will function as initial proton acceptors and whether multiple acceptors can speed proton uptake.
In addition to questions of service uptake, research in pluralistic urban settings must disaggregate information by level of health facility and type of provider across sectors.
This has led directly to the resolution of many outstanding questions regarding the control of uptake and of the pathways and intermediates involved in assimilation.
For further studies it would be extremely interesting to assess the question of clinical relevance of tracer uptake thresholds, to correlate component position with tracer uptake and to elucidate the natural course of tracer uptake before and after TKA.
Previous reports addressed the question of whether LRP1 mediates the uptake of Aβ into neurons.
The question of potential selective mineral nutrient uptake from the xylem is therefore still not conclusively resolved (Bell and Adams, 2011; Tennakoon et al., 2011).
The question of cost-effectiveness for partial uptake rates (i.e. where not every GP participates, or not every eligible patient is screened) is an important one for policy makers.
