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The question of threshold significance is also relevant at this point, and the authors present a simple but appealing approach that assumes that the database contains a few highly matched but many non-matched samples.
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This gets us into the exciting question of thresholds.
To further address this issue, advantage can be taken of scientific advances that have made it possible to address the question of thresholds in a variety of ways.
At our protocol review meeting the question of thresholds for giving radiotherapy (RT) after breast conserving therapy for ductal carcinoma in situ (DCIS) comes up yet again.
The issue of "tolerance" for seeds is separate from the question of the threshold level that would require labeling of foods in grocery stores in countries that require such labeling.
The question of symptom threshold and 'purity' of subtypes is a critical one.
The question of the threshold is still remaining and various studies are in progress to establish a shared EtG concentration level at which alcohol could impact significantly the steroid concentrations.
On the question of prevalence threshold for school closure, these simulations offer no evidence to support school closures promptly at the earliest stage of an epidemic, given the need for an 8-week closure period and the typically unknown transmissibility of the virus during an epidemic.
Yet what is not overtly present in these debates is the question of risk thresholds – when and where do humanitarians draw the line?
In a summary of recent work on the breaking of gravity waves (GWs) and the corresponding onset of turbulence the question of critical thresholds is given a systematic discussion.
Since statistical significance does not necessarily imply clinical or practical significance, many authors have proposed DIF classifications that incorporate both statistical significance and the magnitude of DIF, but once again the question of which thresholds to use is not straightforward.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com