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103 Here again one should take into consideration the question of surrogate versus final outcome parameters.
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Professor David Cameron [ 3] addressed the important questions of surrogate end-points in clinical trials.
When initiating this research, one of the questions was the acceptability of surrogate outcomes (specifically PFS) in the metastatic/advanced cancer setting.
This rank ordering of risk elements for the 2 questions facilitated the calculation of surrogate weights by using the formula where K is the number of elements and Wk is the calculated weight to be applied to each risk element in rank order (10 ).
I'd question the staying power currently of surrogate bond equities like utilities and American Telephone, any stock yielding between 4.5% and 6%.
We addressed this potential bias by performing an independent validation study to determine the accuracy of surrogate information on a number of questions, including the same questions used in this report about NSAID use.
Furthermore, as shown by the examination of Li et al, the appropriateness of surrogate decision has to be questioned [ 16].
Another question to consider when applying our framework is whether the optimal number of surrogate family haplotypes will change with different reference datasets.
He pointed out that Obama's campaign rose "from the middle of the road" and when originally behind with with black communities, there was the question of "was he black enough?" Through surrogates such as BET founder Bob Johnson, the Clinton campaign tried to "blacken him".
There's so much going on: father figures, surrogate father figures, the question of what their relationship really is, the foreshadowing of the moment when Hal decides to banish Falstaff once and for all.
Despite compelling evidence, the crucial question of whether EMSY is a bona fide surrogate for BRCA2 mutation in sporadic cancers still remains to be answered.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com