Our finding raises the question of whether low concordance is the norm in women, and what purpose, if any, concordance serves in human sexual functioning.
An alternative way to address the question of cross-tissue concordance is to ask what is the total amount of genetic variance of transcript levels shared between tissues?
To address this question, we computed the coefficient of concordance, W [ 37], and carried out a right-tailed test to test the null hypothesis that there was no agreement among the rankers (i.e., the participants) against the alternative hypothesis that there was agreement.
We then consider determinants of the degree of concordance in responses to the two questions, as well as the characteristics of individuals that provide conflicting responses.
Microarrays promise much in elucidating the pathogenesis of complex diseases such as PD but the lack of concordance in published data sets to date certainly questions their relevance.
There are open questions about whether data from different microarrays is comparable given low levels of concordance observed between different microarray platforms [ 14, 15].
Given the relevance of non-coding regions in the modulation of gene expression and thus cell stability and function, whether the high level of concordance between genomic and LCL DNA extended to the whole genome remains an important question.
To see whether the degree of concordance vary by household financial stress, we included analyses using two parental perceived financial stress questions.
The companion book is a sort of concordance, ninety-seven pages of notes and dozens of plates of art work.
Kendall's coefficient of concordance.
