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The mean score for the "Communication with Doctor" question increased from the first to second administration, from 1.7 (S.D. = 0.42) to 2.2 (S.D. = 0.41) respectively, and represents a self-reported decrease in communication with doctor.

Although the overall levels of missing data were low in the NorStOP cohort, there was a small, steady rise in missing data from age 50, except for the job done for most of working life question; from age 60, missing data for this question increased from 6% to 17% in those aged 80 and over.

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The mean perception as to whether lecturers could adequately answer participant's questions increased from 4.40 to 4.65 (p < 0.05) in agreement (95% CI 0.34 to 0.45).

Moreover, the proportion of students who used the concept of most recent common ancestry (explanation score of one) to justify a correct evolutionary relatedness response for both questions increased from 0.00 before instruction to only 0.17 after instruction.

The share of children who correctly answered the health questions increased from 17to63percentent immediately after the performance, and had only slightly declined three weeks later.

Median answer time was reduced from 2 days to 1 (p<0.01), although the fraction of complex questions increased from the first to the second period.

Comparing the performance of all GEP students on the pre- and postquiz, we find that the average score for lower-level quiz questions increased from 4.20 5.75 points, while the average score for higher-level quiz questions increased from 1.56 4.4 points (total n = 382 for this matched set).

The scores for the biology concept questions increased from 27.3 to 43.6%, the scores for the predominantly math items increased from 26.3 to 65.7%, and the scores for the integrated items increased tremendously from 28.6 to 83.1% for a normalized g of 0.76.

Concurrently, the average percentage correct for each of the 20 individual questions increased by 13.3% from 52%to65.3%3%.

Correct responses on the 14-question learning assessment increased from 6.32 (standard deviation = 2.36) preintervention to 12.23 (standard deviation = 1.85) post-intervention.

The plasma glucose concentration at which subjects first felt hypoglycemic (answer to the question, "Do you feel hypoglycemic?") increased from 2.6 ± 0.1 mmol/L at baseline to 3.1 ± 0.2 mmol/L post-RCT (P = 0.017).

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