One of the interesting and yet unresolved questions in this process is the impact of nascent peptide compaction (i.e., folding) inside the ribosome tunnel on the stalling mechanism.
One key question in the process, is the choice of sources to search for signals.
The questions asked in this process of analysis are listed as the third stage in the Figure 3.
The questions and the details behind them have been submitted to NIHR and other funders for consideration in their funding programmes, and to date a number of NIHR funding calls have now been based around the questions identified in this process.
The training program is built around health promotion objectives that are measurable and can be evaluated; and the communities or individuals in question are involved in this process of evaluation: assessing local needs, choosing objectives and indicators and evaluating results.
A major new point that came from responding to questions in this review process was the consideration of how the "errant targeting" and biochemical activity of Hairy, as well as potentially many other factors, calls into question our assumptions in calling enhancers from genomics datasets.
Our questions are: 'Where in this process do you need to apply your own judgement?', and then, 'How do you make that decision?' or 'What factors do you have to take into account when making this decision?', and similar conversational questions.
We were interested in identifying where the tacit knowledge was being applied, and the nature of that knowledge, hence the questions like, 'Where in this process do you need to apply your own judgement?' The results are differentiated by operator experience (expert vs. novice).
As implied in the final question of this process, a key to effective two-way coaching is mutual responsibility.
