Next, genes with lower variation across our subjects were filtered out of the gender-adjusted data by selecting only probe sets with an inter-quartile intensity range (IQR) greater than 2000.
For fungicides, there was a significant positive trend for duration of exposure (p-trend = 0.03) with an OR of 2.28 (95% CI: 1.16, 4.50) for the highest quartile; for intensity and cumulative exposure, ORs were significantly increased for the two highest quartiles, but the association was strongest for the third quartile.
For insecticides, there was a significant monotonic association with increasing quartiles of intensity only (p-trend = 0.04) with an OR of 2.04 (95% CI: 1.03, 4.05) for the highest versus lowest quartile.
The risk of tremor-dominant PD increased progressively with quartiles of intensity of exposure to pesticides (p-trend < 0.01; Table 4); the OR was 4.13 (95% CI: 1.53, 11.14) for participants in the highest quartile.
Since the study aimed to compare the effect of armed confict divided into 4 quartiles of intensity, a total of 428 subjects (4 groups with 107 subjects each) would be needed.
Those cases staining in the top quartile of intensities had a median survival significantly shorter than that of the rest of the cohort (145±17 vs 486±55 days, P=0.002; Figure 5A D).
Based on 29 exposed cases of thyroid cancer, there was a statistically significant risk in the second and fourth quartiles of intensity-weighted lifetime days.
The requirement of condoms met through TIs was significantly more in high TI intensity quartile district than in the low TI intensity quartile districts.
To search for genes accomplishing the first condition, we kept only those that had a gene expression measurement above the 3rd quartile of the intensity distribution in all arrays.
The same was done for repeat pairs in each quartile of the intensity difference measure and the shape difference measure.
In high TI intensity quartile districts (n = 30), 186 condoms per FSW/year were distributed through TIs as compared to 45 condoms/FSW/year in the low TI intensity districts (n = 29).
