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Some challenges are computational and result from the huge quantity of sequence data.
Independently of assembly problems, functional annotation is a difficult problem, compounded by the sheer quantity of sequence data.
The goal of the super-read algorithm is to reduce the quantity of sequence data presented to the overlap-based assembler.
Despite research into the behavior and classical and population genetics of this organism, the quantity of sequence data available is limited.
Despite the cost effective advantages a pooled sample approach delivers, given a fixed quantity of sequence data, a compromise on the fold-coverage per pooled sample/group and thereby sensitivity is unavoidable.
With the commercialization of various affordable desktop sequencers, NGS will be reached by increasing numbers of cellular and molecular biologists, necessitating community consensus on bioinformatics protocols to tackle the exponential increase in quantity of sequence data.
Similar(50)
This method allowed the researchers to perform expression profiling and also to increase the quantity and quality of sequence data available for their targeted species, the Chinese hamster [ 17].
Although these sequencing technologies are extremely cost-effective for producing large quantities of sequence data from individual samples, they are not well-suited to producing modest quantities of sequence data from large numbers of samples.
However, the search speed of BLASTX has become insufficient for analysis of the large quantities of sequence data now available.
With the large quantities of sequence data being generated by fungal genome sequencing efforts, high quality functional annotation of biomass-degrading enzymes has become increasingly important.
BAC-FISH can serve as a supporting tool to select BAC clones for sequencing and tagging gene-rich regions in species with low quantities of sequence data.
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