gF appeared to be characterized by genes affecting the quantity and quality of neurons and therefore neuronal efficiency, whereas long-term depression (LTD) seemed to underlie gC.
To be able to characterize brain-derived exosomes, the team leverages a method developed in Church's group, which efficiently cues human induced pluripotent stem cells (iPSCs) along a differentiation program that results in the growth of large quantities of neurons.
DCX haploinsufficiency can lead to various degrees of mental retardation, the extent of retardation is linked to the quantity of arrested neurons in the white matter [44], [45].
Treatment strategies aimed at rhythmogenic Dbx1 neurons may help overcome the effects of a reduced quantity or efficacy of neurons within the preBötC due to neurodegenerative diseases or aging (Benarroch, 2003; Benarroch et al., 2003; Tsuboi et al., 2008).
Here, we focused on monochlorobimane derivatives of GSH measured by fluorescence detection in single live neurons (Kamencic et al., 2000; Ghosh et al., 2012), as quantities of these neurons are insufficient for detection by HPLC.
Meanwhile, the quantities of motor neurons in the anterior horns were significantly increased by simvastatin compared with the vehicle group, p < 0.05).
However, that would be an unreasonable request given that the C. elegans nervous system comprises such a small percentage of the total biomass of the animal and there is no way to dissect out large quantities of worm neurons for such biochemical studies.
Yet, different from parental cells and more similar to immortalized v-IhNSCs, T-IhNSC cells generate a large quantity of well-differentiated neurons, without the need of supplementing the differentiation medium with serum.
