Exact(1)
Here we used in vivo optical imaging of intrinsic signals, which provides qualitatively and quantitatively unbiased measurements of cortical responses to visual stimulation with high spatial resolution in every mouse (Kalatsky and Stryker 2003; Cang et al. 2005).
Similar(59)
Finally, a recommendation is made for study designs that apply a disease-dedicated core assessment protocol (CAP) that can evaluate the period from pre-operative to post-convalescent stages quantitatively, and therefore, unbiased.
This study proposes a largely automated, unbiased method for quantitatively comparing the outputs from proprietary pulse oximeter devices along three metrics: temporal delay, amplification, and complexity.
This can only be done after the term "unbiased" is defined quantitatively in technical terms.
These studies have provided many interesting biological results; however, none of them has demonstrated that the network-based methods for detecting functional modules can significantly outperform the conventional cluster analysis, partially due to the lack of an unbiased metric for quantitatively evaluating the functional significance of gene modules.
Addressing this challenge requires tools that can quantitatively determine the specificities of both individual proteins and multimeric complexes in an unbiased and comprehensive way.
The global transcriptomes of the four groups of mice were compared using a principal component analysis (PCA), which allowed an unbiased analysis in a format in which the groups could be visually and quantitatively compared.
If one stringently follows the unbiased counting rules and has a consistent labeling protocol, it is striking how quantitatively reproducible the results are from one EM grid to the next, and from experiment to experiment by this simple approach.
This article quantitatively describes the spatial distributions of chemically defined GABAergic neurons in the mouse hippocampus by using unbiased stereological techniques.
DIA is an unbiased MS technique and therefore represents a suitable strategy for efficiently generating consistent, reproducible and quantitatively accurate measurements of peptides across multiple samples (Gillet et al., 2012; Collins et al., 2013; Rosenberger et al., 2014; Röst et al., 2014; Guo et al., 2015; Liu et al., 2015; Schubert et al., 2015a).
Referring back to Figure 5, the conformational transitions of both major setups, tmDom and freePP, are compared more quantitatively using the RMSD values, evaluated by using two setups as references, namely, the 200 ns long unbiased simulation freeDyn and a sample trajectory of fullTMD.
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Justyna Jupowicz-Kozak
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