Exact(1)
We have recently applied this knowledge to establish correlations between VIPs and mutation frequencies in cancer genomes (Bacolla et al. 2013), and now expand these relationships to infer quantitatively contributions to mutagenesis in cancer genomes.
Similar(59)
The possibility to quantitatively separate contributions of "chemical" and "mechanical" stabilization components stems from the fact that they affect the first reverse transformation of stabilized martensite through thermodynamically reversible and irreversible factors, respectively.
The purpose of this article is to estimate quantitatively the contribution that university licensing makes to the national U.S. economy.
The objective was to develop and apply a method to assess quantitatively the contribution of planted forests to the world forest economy.
22 Together, these experimental data point to a significant but quantitatively limited contribution of BM to the pool of PSC.
The absolute quantification of AKRs thus makes it possible to globally and quantitatively evaluate contribution of various AKRs to different cancer cell lines.
Therefore it is probable that many other sites of mitochondrial O2− production remain to be discovered, but whether they make a quantitatively significant contribution to mitochondrial ROS production under physiological conditions is unclear [ 1].
Given empirical estimates of the mutational distribution of fitness effects (Eyre-Walker and Keightley 2007), we also show that alleles with sex-differential effects should make a quantitatively large contribution to disease susceptibility within each sex.
To measure more quantitatively the contribution of prednisolone-induced skeletal muscle breakdown in healthy individuals, more invasive measurements such as muscle interstitial 3-methylhistidine concentrations [ 37] could be performed.
Further work is required to establish precisely the nature of the substrate for phloem AsA biosynthesis in vivo and to establish quantitatively the contribution of phloem biosynthesis to the overall AsA content in storage organs.
Nonetheless, those who advocate a quantitatively important contribution of BAT thermogenesis to cold-induced NST point to the calculations of Rothwell and Stock, 50 which are based on data about the high metabolic rate of this tissue in response to norepinephrine in hyperphagic rats exhibiting diet-induced thermogenesis (1.7 mL O2/g/min).
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