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However, some indicators can only reflect quantitative variances rather than quality aspects because of the mathematical characteristics of landscape patterns.
Note also that a similar range of quantitative variances was generated during LRE quantification of eleven cDNA targets [2].
Referred to as the "Av Repl-Fo CV", averaging the quantitative variances generated by all the replicate reaction sets within a run, provided such a general assessment.
Generated during a study investigating the reproducibility of LRE quantification for gene expression profiling, the datasets provided in the demonstration databases focus on assessing the reproducibility of reverse transcription and run-to-run quantitative variances.
Prefractionation, a sample preparation prerequisite that complicates the MALDI analysis, often resulting in sample loss as well as artifactual qualitative and quantitative variances, is therefore not required for SELDI analyses.
Moreover, Figure 6 presents optical calibrations produced by two high-performance lambda amplicons conducted over a 4-month period, which further demonstrates that quantitative variances of less than ±20% can routinely be achieved with LRE.
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Increasing SYBR Green I quantity also did not reduce the quantitative variance of the derived F0 values (see below).
* Nominal P-value 0.05 In addition to quantitative variance ratios from Table 1, we also visualized via dendrograms, that offer a convenient display of highly dimensional data.
Similar levels of quantitative variance were seen across all five reaction formulations as compared with those produced by LRE quantification (Table 1).
Although the monoallelic mechanism of imprinting was first identified in 1984 [ 8], quantitative variance in expression of the two different alleles was only first acknowledged in 2002, in a small study where 6 of only 13 genes investigated showed allelic differences [ 9].
It has been argued that much of the genetic variance associated with common complex disease and quantitative trait variance is likely to be regulatory rather than coding [3].
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