Guo, J. et al. Proteome-wide light/dark modulation of thiol oxidation in cyanobacteria revealed by quantitative site-specific redox proteomics.
Solid state NMR is the primary tool for studying the quantitative, site-specific structure, orientation, and dynamics of biomineralization proteins under biologically relevant conditions.
A major challenge to this project was obtaining quantitative, site-specific supporting data in this re-emerging country that has been in military and internal conflict since 1973.
Finding quantitative, site-specific data for model-input parameters and outcome interpretations in Afghanistan is a challenge similar to those faced in other countries (e.g., Silliman et al. 2007).
In summary, our data reveal quantitative site-specific changes in tyrosine phosphorylation induced by CSF-1R activation in epithelial cells and identify many candidate SRC-dependent substrates phosphorylated downstream of an RTK.
Quantitative site-specific dynamics measurements reveal that, despite their stabilizing role and supramolecular interactions, the httNT α-helices outside this amyloid core undergo molten-globule-like motions.
Using a tiered focusing approach, our strategy proceeded from unbiased broad DNA methylation analysis using methylation-based next generation sequencing technology to in-depth quantitative site-specific CpG methylation determination using the Sequenom EpiTYPER MassARRAY platform.
We present a workflow for quantitative site-specific analysis of fucosylation and apply it to a comparison of hemopexin (HPX) and complement factor H CFHH), two liver-secreted glycoproteins, in healthy individuals and patients with liver cirrhosis and HCC.
We have demonstrated the quantitative site-specific labelling of proteins bearing a genetically incorporated BCN with phenyl sydnone 1 and PheSyd BODIPY-FL 6 in aqueous buffer at 37 °C and demonstrated that the reaction is chemoselective with resPheSyd BODIPY-FLoli proteome.
The authors have developed the first analytical method based on a portable luminometer, specifically designed and validated to locate IE manufacturing sites using quantitative on-site vapour analysis for H2O2.
