Sentence examples for quantitative probes from inspiring English sources

The concept of atoms thus emerged from the meticulous measurement of mass and volume, which in the earliest days of chemistry were the only quantitative probes of matter available.

Somewhat more specific and quantitative probes of P-glycoprotein transport have been developed for PET imaging [ 137- 139].

We conclude that the calibrated BOLD approach provides a highly reproducible measurement of n that can serve as a useful quantitative probe of the coupling of blood flow and energy metabolism in the brain.

Examples of continuous segmentation include methods that essentially average over quantitative probe values within a genomic region determined by the algorithm to be a copy number segment.

Raman microspectroscopy allows quantitative probing of dynamic macromolecular landscape at the single organelle level, and thus identifying the mitochondrial function at normal physiological and stress conditions.

Therefore, the applicability of an intracellular biosensor as a quantitative probe needs to be evaluated and calibrated separately for each organism and condition to achieve reliable data.

Alternately, quantitative probe measurements may be used directly, although the reader is advised to read the material on Probe Bias in DNA Copy Number Data in Section 2.4 before analyzing individual probe-level data.

These smaller CNVs that went undetected by SNP microarrays were missed due to insufficient probes coverage at these loci and because of the lower signal-to-noise often observed for SNP array platforms (e.g., SNP-based arrays are optimized for robust genotyping call rates, which may minimize quantitative probe response to copy number variation).

We recommend the following bias-correction procedure when working with data matrices X that contain quantitative probe-level data: Algorithm 3. Removing Probe Bias Use a segmentation algorithm to get Seg(X ), a segmented version of X. Compute Resid(X ) = X − Seg(X ).

Previously, we have shown that mitochondrial ROS is a main trigger for neuronal loss in cells with a complex I defect, and that oligomeric α-synuclein can induce cell death through induction of lipid peroxidation, therefore, we assessed the rate of hydrogen peroxide (H2O2) production, using the Hyper-3 genetic quantitative probe.

We describe the use of ssDNA functionalized silver nanoparticle (AgNP) probes for quantitative investigation of biorecognition and real time detection of biomolecular targets using nano-impact electrochemistry.