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Eighty-three patients were felt not to have significant mismatch on visual perfusion CT assessment yet did fulfil quantitative mismatch criteria.
The absence of appropriate human resources policies is responsible, in many countries, for a chronic imbalance with multifaceted effects on the health workforce: quantitative mismatch, qualitative disparity, unequal distribution and a lack of coordination between HRM actions and health policy needs.
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When MIBG uptake was corrected for perfusion abnormalities, diabetic patients had a greater MIBG uptake defect than normal subjects on visual score assessment (16 +/- 13 vs. 8 +/- 7%, p = 0.0002) and on quantitative MIBG mismatch assessment (13 +/- 15% vs. 2 +/- 2%, p = 0.0001).
Our data suggested that patients with absence of a quantitative target mismatch did not benefit from treatment.
Of the 366 patients treated with rtPA based on combined clinical, non-contrast CT and qualitative on-line perfusion CT criteria, 253 (69%) met the quantitative 'target mismatch' criteria.
The results of the entire JHH cohort selected based on visual perfusion CT assessment are much less compelling than the quantitative target mismatch group comparison.
Eighty-three patients (31%) of the 269 patients excluded from rtPA treatment based on qualitative perfusion CT grounds also fulfilled quantitative target mismatch criteria.
Apart from younger age in the treated group (P = 0.023, a factor which, ordinarily, might be expected to favour this group), baseline characteristics were similar between the treated and untreated patients not fulfilling quantitative target mismatch criteria (Table 2).
> -wrap-foot> Similar findings were seen in the comparison of the rtPA patients with confirmed off-line quantitative target mismatch and the historical rtPA-treated non-perfusion CT selected controls (Table 4 and Fig. 3).
It is possible that these factors may be able to add value to the quantitative perfusion CT target mismatch criteria applied in the current study.
A further 57 patients were treated as on-line evaluation of perfusion maps suggested visual perfusion CT mismatch; however, quantitative off-line analysis showed that they did not achieve target mismatch criteria.
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