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All in all, our results not only confirm that mastermind, invected, cricklet and CG14591 are quantitative candidate genes for developmental time expression, but also that these genes exhibit natural allelic variants that contribute to natural variation in DT.
In addition, experts were asked to suggest cut-off points for the proposed quantitative candidate criteria items based on data from the literature review.
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Using gene expression and sequence information, we suggest Rsad2 (viperin) and Colec11 (collectin-11) on chromosome 12 as potential quantitative trait candidate genes.
The genes encoding the radical S-adenosyl methionine domain containing 2 (Rsand) and collectin sub-family member 11 (Colec11) matched with the criteria for potential quantitative trait candidate genes, e.g. location of the gene in the QTL region, expression in the target tissue, density of non-synonymous (ns) SNP and InDels, cis-regulation of expression, and known or presumed gene function.
Thus Nln is an attractive candidate quantitative trait gene (QTG) and this SNP is an attractive quantitative trait nucleotide (QTN) for further mechanistic studies of Nln involvement in glucose metabolism.
Quantitative trait loci, candidate genes and associated genetic markers for these traits have been identified and located in the turbot genome.
To develop a prospective method for optimizing seizure prediction, given an array of implanted electrodes and a set of candidate quantitative features computed at each contact location.
While a wide range of other policy, environmental, and engineering issues will remain important to transmission planning, the methods here will enhance planning by providing quantitative ranking of candidate network additions with respect to overall transmission system performance.
In order to indentify candidate quantitative phenotype genes, we resequenced the Socs2 and Nudt4 coding regions and genotyped SNPs within the MMU10 locus (Figure 3B).
Data showing that a clusterin knockout mouse inoculated with BSE prions has a significantly increased incubation time suggested that Clu was a particularly good candidate quantitative trait gene for prion disease incubation time [25].
Three candidate quantitative trait nucleotides were identified in PKS1.
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