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Considering that 8 TMT channels allow the determination of 28 binary comparisons, the quantitative breadth of these analyses entails 172 704 quantitative protein abundance ratios measured in all three biological replicates.
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But even in its quantitative perspective and breadth, the book still stands on the shoulders of an economic classic, "A Monetary History of the United States: 1867-1960," written by another great male-and-female pair of economists, Milton Friedman and Anna Jacobson Schwartz.
To achieve similar breadth of quantitative analysis, including eight samples and three biological replicates, would require 24 separate experiments using a simple duplex quantitative method (e.g., SILAC).
In his welcome, Bruce Walsh (University of Arizona, USA) illustrated the breadth of quantitative genetics by asking for a show of hands as he listed various areas of interest.
The qualitative type of data gives greater depth, while the quantitative data gives greater breadth; together it yields results from which one can make better inferences [ 17].
The geographic breadth of quantitative studies was limited: 53% (8/15) of the studies were conducted with asylum-based refugees and IDPs in African settings.
However, these studies didn't directly interrogate the interaction of the nuclear and cytoplasmic genomes for quantitative traits or test the breadth of phenotypes affected.
Quantitative proteomic analysis revealed a wide breadth of signaling events during transition to acquired tamoxifen resistance.
These included determining the breadth of evidence needed (quantitative or qualitative or both) and balancing this need with the feasibility or resources available to perform the review, anticipating the end-users of findings, and to what extent the method provides strategies for rigor and transparency.
Further, our survey included both quantitative and qualitative components to increase the breadth of findings we could examine.
Mixed methods can reap the advantages of breadth and generalizability obtained from quantitative methodologies, and also the depth in understanding phenomena from qualitative methodologies.
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