Some experts have suggested that benefits be quantified using quality-adjusted life-years saved (65).
While it is not surprising that an externally supported project resulted in improved care-seeking as compared with the existing national CHW strategy, these differences are now quantified and suggest that the approach used under Kabeho Mwana can be useful in improving CHW performance, and possibly improve the cost-effectiveness of performance-based financing.
The impact of selected individual risk factors on geographical differences in all-cause mortality for Australia has been recently quantified and suggests that interventions targeted at modifiable health factors could translate to a substantial reduction (around 36-45%) in the regional mortality differentials [ 49].
Infection of C2C12 cells with either Pax3DN RV or Pax7DN RV dominant-negative constructs led to a rapid (within 24 h) and significant (p<0.0001) reduction in the proportion of cells expressing either MyoD or myogenin protein (Figure 3d and e, quantified in p), suggesting that although all C2C12 cells lack Pax3, Pax transcriptional targets are normally activated.
However and inconsistent with this view, total Tau levels were not significantly altered (Fig 1C and quantified in 1F), suggesting that the pTau pool may represent only a small pool of total Tau levels or that TFEB might also act on Tau phosphorylation/dephosphorylation.
What fool suggested that?
While these disservices are highly variable and difficult to quantify, results suggest that factors such as soil and sediment texture, oxygen, and nitrate levels influence fluxes in a systematic way that should allow for the development of assessment and accounting protocols to account for ecosystem services and disservices associated with nitrogen flows in complex landscapes.
In this study we only observed and quantified MAP1B (Figure 4), suggesting that MAP1B is more abundant than the other two amino peptidases.
Also at the tumor periphery, Collagen I protein levels were significantly increased in MMP13 KO versus wildtype animals as quantified by immunofluorescence staining, suggesting that depletion of this collagen degrading enzyme from host cells increases tumor Collagen I content.
Yet, phospho-Vpu-dependent CD4 degradation is almost completely lost (quantified in Figure 1D), suggesting that even small decreases in interaction are sufficient to effect a large change in degradation.
