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Segmental motion was quantified as the change in the intervertebral angle between the resting and end-range vertebral positions.
Evolution and decay of the intermediate, [SF*][A], was quantified as the change in the fluorescence level of zyxin or paxillin.
Response magnitude was quantified as the change in average firing rate during the 40 s following stimulus presentation relative to the firing rate during the 20 s prior to stimulus presentation.
For a fixed genotype, plasticity can be quantified as the change in phenotype when the environment is varied (for a binary phenotype) or the slope of the phenotype environment curve (for a continuous phenotype variable) (Scheiner 1993; Pigliucci 2005; Bergland et al. 2008).
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The arterial dilatation, quantified as the percent change in arterial diameter, reflects local endothelial release of nitric oxide (NO).
Bias was quantified as the proportional change in the mean starting point (∆ z/z; for details see Mulder et al. 2012).
To characterize changes with treatment, differences in signal were quantified as the log2 fold change (log2 (treated/untreated)) and hierarchical clustering was performed using these values.
Response magnitude was quantified as the percentage BOLD signal change for each pitch condition relative to the noise control and was measured in each of the individual pitch regions reported in Table 1.
For this study, the patient's response during a given trial was quantified as the greatest (positive or negative) change in blood volume from the moment of trial onset.
Signals were then quantified as the background-subtracted fluorescence intensity changes normalized to the background-subtracted baseline fluorescence using Image J software.
In addition, within the 31 comprehensive measurements, change was quantified as the absolute difference in SC CSA between adjacent B-scans within each volume.
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