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The best example of such a concept is the quantification of insulin sensitivity, as defined by the insulin sensitivity index.
The quantification of insulin resistance is desirable in clinical practice since this metabolic state is a treatable precursor of diabetes mellitus [ 14].
Figure 4 depicts one strategy for visually monitoring insulin granule movement and exocytosis, and for providing instantaneous quantification of insulin secretion.
Accurate quantification of insulin resistance is important for diagnosing and determining the efficacy of treatment in patients with equine metabolic syndrome (EMS).
After 1 h, medium was recovered for quantification of insulin and serotonin release using commercial ELISA kits (LDN, Nordhorn, Germany; Mercodia, Uppsala, Sweden, respectively).
Although insulin resistance is regarded as the aetiological mechanism underpinning MS, direct quantification of insulin sensitivity can be difficult and complex in the general population.
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Before measurement of GSIS the culture media were collected and frozen for quantification of accumulated insulin secretion.
Participants completed standardized medical history questionnaires ascertaining medication use and previous diagnoses and provided samples for quantification of fasting insulin and lipids (8).
Quantification of MKi67-insulin double positive cells was performed at ×400 magnification by two independent observers.
Quantification of the insulin-positive area in Ngn3 conditional transgenic mouse pancreas was performed on NanoZoomer 2.0-HT (HAMAMATSU) scanned slides using AdobePS-CS5.
(B ) Quantification of intensity of insulin receptor β, Igf1rβ, Irs2 (Image J).
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