Cell proliferation (detected by IHC for Ki-67 followed by automated quantification) was reduced to an equal extent in BKM120-treated tumors and with the combination treatment, but not in PD0325901-treated tumors alone (Fig. 6B,C).
When the amount of collagen fibrils is reduced, as shown with hydroxyproline quantification, this effect would not be as pronounced, and the Pif might be reduced.
But this is not to commit to the claim that propositional quantification is to be reduced to objectual quantification over sets of propositions or sets of possible worlds or what have you.
This quantification limit could be reduced by filtering a larger sample volume, which would increase the sensitivity of the qrt-PCR assay.
Specifically, the addition of the detector case led to a drop of 27% in the absorption coefficient estimate for a single wavelength in the resin phantom, and a 23% drop in total hemoglobin recovered in the background of the inclusion phantom, indicating that the accuracy of absorption quantification is significantly reduced when the case was present.
Confidence in quantification of Ra mass balance was reduced by study design limitations, including synoptic sampling of effluents and ground waters, and large uncertainties associated with analytical methods.
Western blot quantification revealed that RalA level was reduced by about 50% in cells expressing the RalA shRNA.
Phantom experiments demonstrated that an average quantification error of –18.7% was reduced to –1.7% when both window-based scatter correction and Chang correction based on the body outline from optical images were applied.
However, due to a relatively large capacitive current, which decays slowly, the limit of quantification for such microelectrodes has only been reduced by one half with respect to that of the HMDE.
We included quantification indicating that Spo11 protein levels are reduced at least 10-fold upon HU treatment, which likely reduces overall DSB activity.
