Sentence examples for quantifiable time point from inspiring English sources

was calculated as the sum of AUC0– t and the extrapolated area under the zero moment curve from the last quantifiable time point to infinity calculated by dividing the plasma concentration of the last quantifiable time point (observed value) by the elimination rate constant.

AUC0-∞ was calculated as the sum of the area from time zero to the last quantifiable time point t obtained by the trapezoidal method, and the area from t to infinite time calculated from Ct/λz; Ct is the last observed quantifiable concentration.

Pharmacokinetic parameters included Cmax, tmax which were determined directly from the plasma concentration-time profiles of each, and area under the plasma concentration curve from zero to the last quantifiable time point (AUC0 tz), calculated using the linear trapezoidal method for ascending concentrations and the log trapezoidal method for descending concentrations.

The area under the concentration (AUC time curve from time zero up to the last quantifiable time point (AUC0– t ) was calculated using the linear trapezoidal rule, and the area under the concentration time curve from zero until infinity (AUC0 inf).

The pharmacokinetic parameters of maximum plasma concentration (Cmax), tmax (time to Cmax), half-life (t1/2z), area under the curve at the last quantifiable time-point (LIXI-AUClast) and LIXI-AUC were calculated using non-compartmental methods from plasma concentration data of LIXI, and were summarized by descriptive statistics.

For treatment cycles with sufficient figitumumab PK data, area under the plasma concentration time curve (AUC) from time 0 to the last sampling time point with quantifiable concentration within a cycle (AUClast) and from time 0 to the last day of a cycle (AUC0 day22) were determined using the linear/log trapezoidal approximation.

Negative-sense RNA was not detectable until 2 hr post infection for MOIs 10 and 100 and 3 hr post infection for MOI 1. Positive-sense RNA was clearly quantifiable for all time points at the MOI 10 and 100 but did not rise above background levels until 3 hr post infection for MOI 1.

The AUC was calculated according to the following equation: AUC= +(computed Clast/ λz), with computed Clast being the concentration calculated for the time point (tlast) with the last quantifiable concentration, and λz being the terminal disposition rate constant.

Importantly, this approach minimizes the number of animals required, particularly in comparison with single time point studies requiring animal sacrifice for quantifiable outcome measures.

There was 4-fold greater DA retained in milk than plasma at the 8-hr time point, and 3 ng/mL DA still quantifiable at 24 hr, whereas DA was only detectable in plasma at 24 hr.

Only two patients had a quantifiable level of Aβ-specific IgGs in CSF, each at one time point during the studies.