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Both diagnostic peptides for PtdIns5 P 4-kinase IIα were detected and the protein was quantified at 1.5 pmol/mg of total protein, but no quantifiable signals were detected for PtdIns5 P 4-kinase IIβ.
We show that these constructs 1) respond as expected to endogenous zebrafish hormones and cofactors, 2) facilitate efficient receptor and cofactor purification, 3) respond robustly to NR hormones and drugs and 4) yield readily quantifiable signals.
Two transitions were monitored for each peptide across the selected first-dimension fractions by UPLC SRM and quantifiable signals with acceptable signal-to-noise response were integrated.
These observations demonstrate that sequencing barcode pools results in linear, quantifiable signals whereas microarray detection displays nonlinear signal, a behaviour previously observed by Pierce et al. [ 27].
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Dr Miller thought lap-dancing clubs a good place to study this arms race, because male detection of female fertility cues would probably translate into an easily quantifiable signal, namely dollars earned.
Furthermore, a biosensor requires also a transduction mechanism by which the detection of the analytes becomes a measurable and quantifiable signal.
Label-free biosensing devices can incorporate different specific recognition elements, such as antibodies, DNA molecules, or enzymes that convert the reaction with a given analyte into a quantifiable signal such as an optical, acoustic, electrochemical, or mass change [2, 5].
Genetically modified bacteria, engineered to generate a quantifiable signal in response to pre-determined sets of environmental conditions, may serve as combined sensing/reporting elements in whole-cell biosensors.
transforming the biorecognition event into a more simple and quantifiable signal.
No quantifiable signal was observed for Gln at FV above 120 V; only pGlu was detected in that range of fragmentor voltages.
These instruments will provide us with accurate diagnoses thanks to the sensitive and quantifiable signal of PET and the high soft-tissue resolution of MRI.
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