Focus on quantifiable models of neural signaling, starting with physical specification of input signals, sensory transductions, spiking, and mean electrical field potentials, and the inter-relation to BOLD signals (fMRI).
Furthermore, quantifiable models of spontaneous or induced lymphatic sprouting into the tadpole fin were developed for dynamic analysis of loss-of-function and gain-of-function phenotypes using pharmacologic or genetic manipulation.
Alfred R Allen between 1908 and 1911 developed a reproducible and quantifiable model that allowed induction of a uniform traumatic injury to the spine, and also explained the pathophysiological changes seen in spinal trauma, including key aspects of secondary spinal cord injury.
A quantifiable model cell system shows that intracellular delivery of even moderate levels of iron oxide (Fe2O3) nanoparticles may adversely affect cell function.
Using a quantifiable 2D-model of tubulogenesis, we established that EG-VEGF strongly promotes HPEC morphogenesis into tube-like structures [ 42– 42].
In order to investigate whether serum ProCT levels might correlate with the severity of illness in sepsis, and thus might provide a convenient marker, we employed a rodent model of quantifiable Escherichia coli peritonitis, modified for use in the hamster [ 18].
The mouse model of MPS IIIB has several quantifiable phenotypic alterations and is similar to the human disease.
Distal hypoxic stroke: a new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit.
UML, however, provides a very abstract and highly idealized model of time; it does not even define a basic quantifiable unit of physical time.
The purpose of this study was to develop a novel isogenic rat model of impaired vasculogenesis of the regenerate mandible in order to determine quantifiable metrics of vascular injury and associated damage.
