By analogy with the CFST model, each possible exposure threshold is a different susceptibility type; therefore, the continuous quantal model contains an infinite number of possible types.
Results on the pharmacological effects of oxotremorine and muscarine on quantal ACh release in wild-type and M2 receptor knockout provide biological data for which the negative autoreceptor coupling parameters were calibrated.
The quantal spectral sensitivity of each cone type in both juvenile and adult lungfish was calculated as the product of outer segment axial absorptance, oil droplet or ellipsoidal/paraboloidal pigment axial transmittance and ocular media transmittance [ 61].
Reflectance spectra of lungfish colours and other relevant objects, measured relative to a white standard as described above, were multiplied by the downwelling irradiance spectrum (habitat light) and then multiplied by the quantal spectral sensitivity of each cone type.
Peled, E. S. & Isacoff, E. Y. Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons.
Quantal content was compared between female wild-type and ASIC1a −/− MNTs (0.8 mM HEPES-based saline solution containing 2 mM [Ca2+]/1 mM [Mg2+] + 10 μM μ conotoxin GIIIB), during low-frequency nerve stimulation (direct method, corrected for nonlinear summation, see materials and methods).
Following the equation of Vorobyev et al. [ 31], absolute quantal catch rates of the four cone receptor types (UV, S, M, L) were calculated by multiplying the reflectance spectrum of each body region by the spectral sensitivity of the cones and the irradiance spectrum of the fluorescent tubes summed across wavelengths between 300 and 700 nm.
We have previously formulated the relation between dose and quantal response for the extreme forms of this type of joint action, namely, simple similar action1, in which the drugs act on the same physiological system, and independent action1,2, in which they act on different systems.
Quantal emission rate was constant, independent of the type of stimulation and of the postsynaptic membrane potential level; it was higher in the K+-enriched solution (30 65 mEPSP/s) than in hyperosmotic conditions (27 32 mEPSP/s).
In strains coexpressing UNC-13S and UNC-13L, quantal content was slightly larger than in wild-type controls, whereas activation and decay kinetics were not significantly altered (G and H ). Changes in the intrinsic kinetics of muscle ACh responses cannot account for changes in evoked EPSC kinetics.
