Sentence examples for quantal effects from inspiring English sources

However, not all quantal effects may be derived from applying a cut point to an underlying continuous variable.

In this context, the apical effects under discussion are quantal effects—ones that are either present or absent— rather than continuous measures such as blood pressure or liver weight.

The report produced by a Committee on Improving Risk Analysis Approaches Used by the USEPA also defined a risk-specific reference dose (for quantal effects) as "the dose that corresponds to a particular risk specified to be de minimis (for example, 1 in 100,000) at a defined confidence level (for example, 95%) for the toxicity end point of concern".

For a stochastic quantal endpoint, this equals the expected population incidence of the quantal effect.

In addition, the sigmoidal dose response curve often produced by quantal data (apical adverse effects) in linear space occurs as a result of the variability in individual responses and underlying genomic plasticity, reflecting differences in sensitivity to a given chemical.

Nonetheless, the EPSC is intrinsically a compound phenomenon, strictly related to the summed effect of quantal transmitter packets, whose single size is not readily measurable.

By contrast, inactivating Tomosyn in UNC-13L-rescued animals had more modest effects on the quantal content (96% increase, p<0.001).

Collectively, these results suggest that the FRM-3 and NLG-1 scaffolds increase the diversity of quantal responses, and that this effect cannot be explained by changes in synaptic UNC-49 levels nor by changes in mean mIPSC amplitude.

Another conceptual issue related to stochastic quantal endpoints concerns the definition of a toxicologically equivalent effect metric for individual probability of effect (e.g., of malformations or cancer).

Consistent with this idea, the effect of EGTA on the quantal content of evoked EPSCs was virtually eliminated in UNC-13L-rescued animals, indicating that SVs primed by UNC-13L bind calcium more rapidly than in wild-type controls.

We have given a possible dynamical systems explanation of the chaotic quantal slowing down of inspiration observed under the effects of opiates in rats.